N-PHENYL-2-NAPHTHYLAMINE (Group 3) A. Evidence for carcinogenicity to humans (inadequate) No excess of bladder tumours was found among men in a rubber processing factory with known exposure to N-phenyl-2-naphthylamine (which contained small amounts of2-naph-thylamine (see p. 261)); however, a study of rubber workers who were not exposed to
Use of chlorophyll a fluorescence to elucidate the toxicity target of N -phenyl-2-naphthylamine on photosynthetic system of Cylindrospermopsis raciborskii (Cyanobacteria)
Evidence for an Increase in Microviscosity of Plasma Membranes from Soybean Hypocotyls Induced by the Plant Hormone, Indole-3-Acetic Acid . bound probe N-phenyl-1-naphthylamine…
acid (16-AP) bound to egg phosphatidylcholine vesicles or dissolved in nonpolar solvents. . 2-NPN, N-phenyl-2-naphthylamine; 1-NPN, N-phenyl-l-naphthylamine; 12-AS, 2-AS, n-AS are, . Measurements were also made using a blank containing all components except the probe, andwhennecessary, appropriate corrections for scattering contributions
Metabolic dephenylation of the rubber antioxidant N-phenyl-2-naphthylamine to carcinogenic 2-naphthylamine in rats . 5 f 24 h trifuged for 10 min at 1,200g to remove the cell debris. The supernatant was drawn off, and 20 mL ethanol was added 5 m; 5 f 48 h rapidly under vortex mixing to precipitate haemoglobin. . This study was designed to .
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N-Phenyl-1-naphthylamine for synthesis. CAS 90-30-2, pH (H₂O) neutral. - Find MSDS or SDS, a COA, data sheets and more information.
cerevisiae T 158 C was investigated with a fluorescent probe N-phenyl-1-na phthylamine (NPN). After the toxin was added to sensitive cells the probe fluorescence increased. The largest increase in intensity was observed at 430 nm. It depended particularly on toxin concentration, ageing of …
The amounts of analytes spiked (2.164 µg of N-phenyl-1-naphthylamine and 2.153 µg of N-phenyl-2-naphthylamine) are equal to the target concentrations. The filters were then assembled in cassettes and 240 L of air at approximately 80% relative humidity and 21°C were drawn through each sampling device.
Although data concerning the formation of this metabolite are not available for N-phenyl-1-naphthylamine, it should be noted that, based on its chemical structure, it is unlikely that N-phenyl-1-naphthylamine is metabolized to 2-naphthylamine.
N-Phenyl-1-naphthylamine is a lipophilic white to slight brownish crystalline powder that is used as an antioxidant in various in rubbers and lubrication oils. It is also used as an itermediate for vulcanization accelerators, dyes and other organic chemicals.
1-Naphthylamine is an aromatic amine derived from naphthalene. It can cause bladder cancer (transitional cell carcinoma). It crystallizes in colorless needles which melt at 50 °C. It possesses a disagreeable odor, sublimes readily, and turns brown on exposure to air. It is the precursor to a …
Dec 06, 1976· An evaluation of N-phenyl-1-naphthylamine as a probe of membrane energy state in Escherichia coli. Cramer WA, Postma PW, Helgerson SL. Colicin El and the uncoupler of oxidative phosphorylation, trifluoromethoxy-carbonylcyanidephenylhydrazone (FCCP), cause an increase in the fluorescence intensity of N-phenyl-1-naphthylamine bound to whole cells .
1. Colony: group of cells (visible as a small spherical mass on solid media) resulting from a single spore or vegetative cell, or from a group of the same microbe attached in chains or clumps.: individual bacterial colonies can be isolated using the streak plate method for …
Jun 22, 1987· 1. FEBS Lett. 1987 Jun 22;218(1):22-6. The fluorescence intensity of the lipophilic probe N-phenyl-1-naphthylamine responds to the oxidation-reduction state of the respiratory chain in everted membrane vesicles of Escherichia coli. Sedgwick EG, Bragg PD.
N-Phenyl-l-naphthylamine (NPN), a reagent which has been used previously to probe the fluidity or microviscosity of the membrane lipids of intact cells of Escherichia coli, was found to respond to the redox state of purified eytochrome o incorporated into lipid …
N-Phenyl-1-naphthylamine (P 1 NA) and N-Phenyl-2-naphthylamine (P 2 NA) are both widely used as antioxidant and plant secondary metabolites. In this study, growth, esterase, photosynthetic activity and cell membrane integrity were used as biomarkers to compare biotoxicity of P 1 NA and P 2 NA on Microcystis aeruginosa .
icity of N-phenyl-1-naphthylamine after repeated daily oral administration for 28 days and examined the plastici-ty of the effects in the 14-day recovery period. This study was designed to meet the test guide-lines for toxicology studies issued by "Notiﬁcation test methods of …
A metabolite of N-phenyl-1-naphthylamine, α-naphthylamine (CAS no. 134-32-7) is mutagenic to Salmonella but does not induce MN in mice (Sasaki et al., 1999). The alkaline single cell gel electrophoresis assay (Comet assay), which detects DNA lesions, produces a positive response in the bladders of mice treated with α-naphthylamine.
Effect of the treatment of soybean nodules with nitrate on the permeability of the outer membrane of bacteroids of Bradyrhizobium japonicum strain 138NR was examined using the hydrophobic fluorescent probe N-phenyl-1-naphthylamine (NPN).
Gewinnung und Darstellung. N-Phenyl-2-naphthylamin kann durch Reaktion von 2-Naphthol mit Anilin-Hydrochlorid gewonnen werden, was bereits 1880 von Carl Graebe veröffentlicht wurde.. Eigenschaften. N-Phenyl-2-naphthylamin ist ein brennbarer schwer entzündbarer fast farbloser geruchloser schuppiger Feststoff, der praktisch unlöslich in Wasser ist und sich an Luft nach grau-rosa verfärbt.
Figure Lengend Snippet: Binding of PregOBP56a to N -phenyl-1-naphthylamine (1-NPN) and potential ligands derived from chicken meat. A, A typical emission spectra following the addition of 1-NPN (3.2–16 µM final concentration) to recombinant PregOBP56a (10 µg/ml of 20 mM phosphate-citrate buffer, pH 7).
N-Phenyl-1-naphthylamine was used as hydrophobic probe to study the phase transitions of membrane lipids in whole cells . Packaging 500 g in glass bottle Biochem/physiol Actions N-Phenyl-1-naphthylamine turns fluorescent after binding to hydrophobic regions of cell membranes.
3472 HAN ET AL. Journal of Dairy Science Vol. 96 No. 6, 2013 exhibits moderate antimicrobial activity against Esch- erichia coli, Staphylococcus aureus, and Candida albi- cans through a mechanism .
Description N-Phenyl-1-naphthylamine 98% (250g) More About this Item Chemicals sold by Cole-Parmer are not intended for and should not be (i) used for medical, surgical or other patient oriented applications, or (ii) combined with any food product or ingested in any form.
in intact LM cells was 0.218 f 0.009 while in phagocytosed latex bead membranes the polarization was 0.248 0.006. Second, trans-parinaric acid, 1,6-diphenyl-1,3,5-hexatriene, and N-phenyl-l- naphthylamine were used as fluorescent membrane probes in isolated plasma membrane vesicles.
Brusick D, Matheson D (1977) Mutagenic evaluation of 1,1-dimethylhydrazine, methylhydrazine and N-phenyl-alpha-naphthylamine.In: Proceedings of the 7th annual conference on environmental toxicology, 13-15 October 1976. Wright-Patterson Air Force Base, OH, Aerospace Medical Research
N-Phenyl-β-naphthylamine. Ca* See Appendix A [*Note: Since metabolized to β-Naphthylamine.] White to yellow crystals or gray to tan flakes or powder. [Note: Commercial product may contain 20-30 ppm of β-Naphthylamine.]
1-Naphthylamine. 1-Naphthylamine is an aromatic amine derived from naphthalene. It can cause bladder cancer (transitional cell carcinoma). It crystallizes in colorless needles which melt at 50 °C. It possesses a disagreeable odor, sublimes readily, and turns brown on exposure to air. It is the precursor to a …
Page 1 of 1 . PANA (N-Phenyl-alpha-naphthylamine) CAS No. 90-30-2 . HN. PANA (N-Phenyl-alpha-naphthylamine) is a high-purity product widely used as an antioxidant in petroleum products, synthetic lubricants, rubber products, and as an organic intermediate.
Three established methods utilized to measure polysorbate 20 were evaluated for their ability to detect degraded polysorbate 20. These methods were: (1) fluorescence analysis with N-phenyl-1-naphthylamine fluorescent dye; (2) UV spectroscopy with ammonium cobaltothiocyanate colorimetric reagent; and (3) nuclear magnetic resonance (NMR). Results.